项目英文摘要

Hospital Technology Innovation Award of Chinese Hospital Association

Summary of Recommended Project

(ENGLISH)

Project Name: A relationship study of right ventricular function and lung function in patients with essential hypertension by a new modified method of two-dimensional echocardiograph

The first person and unit name to complete the project: the first person is Dengjie and the unit is Yan’an hospital of Kun Ming

The beginning and ending years of project: september 2005 to december 2009

The source of research project funding : self-funding and appropriation of Kunming Science and Technology Agency

Project Description: (800-1000 words)

Due to the irregular and asymmetrical right ventricle, it either has a substantial error to measure right heart function by using normal ultrasonic way, or can’t be put into wide use mostly for technological or economical reasons by using the invadable or specific ultrasonic ways, such as transeasophageal three-dimensional echocardiography.To explore a relatively accurate method of right ventricular volume by two- dimensional ultrasound, and seek to get the more accurate indictors of right ventricular function on the basis of transthoracic two-dimensional ultrasound examination.The method of research was automatic detection and recognition of the right endocardial and measurement right ventricular function by computer endocardial automatic identification technology. Combined with modified Simpson method (hereinafter referred to as improved ultrasound analysis), evaluated the right ventricular function of essential hypertension patients, and contrasted with the control group. The research has discussed the affects of essential hypertension on right ventricular function, at the same time studied the relation between right ventricular ejection fraction (RVEF) and conventional indicators of lung function which obtained forced vital capacity (FVC), maximum voluntary ventilation (MVV), residual volume (RV) and so on. The results showed that 1. Improved ultrasound analysis was feasible and accurate measurement for estimating right ventricular function of essential hypertension patients with simple, sensitive features and good repeatability, and provided a new valuable and practical method for clinic; 2. Right ventricular systolic function was damaged, the third degree essential hypertension patients significantly; 3.There was damaged of lung ventilation function in patients with essential hypertension which aggravate with increase of blood pressure level; 4. There was correlation between RVEF and lung ventilation function in patients with essential hypertension. The invention and innovation of this research mainly in: 1.Modified Simpson method of the research which used the traditional simpson method to calculate the ventricular cavity volume (including the left and right ventricle and interventricular septum) and left ventricular volume (including the septum), then got the right ventricular cavity volume after the two-phase subtraction, and further calculated the right ventricular function. the same literature has not yet seen in public reports. 2. Although there have been the study of lung function in patients with essential hypertension in our country, but has not yet seen the report on the corrlelation study between right ventricular function and lung function in patients with essential hypertension.3.The study showed that improved ultrasound method was feasible and accurate measurement for estimating right ventricular function of essential hypertension patients with simple, economic, sensitive features and good repeatability. It is due to improved ultrasound method is more accurate and repeatable than the traditional method, combined with the other advantages included that its demands on the equipment is not expensive and echnology promotion is not difficullt,therefore it has good prospect for wider application, good economic returns and social benefits.The subject was programmable topic in Kunming Science and Technology Agency. After several years of research, end of the topic in January 26, 2010, and through the identification by the Provincial and municipal experts, these experts considered that the study has reached domestic leading level and agreed acceptance unanimously. The subject was the third place in Kunming Science and Technology Award in June, 2010.